- Cln Mutants
- cln1∆ cln2∆
- cln1∆ cln2∆ sic1∆
- cln1∆ cln2∆ cdh1∆
- cln1∆ cln2∆ bck2∆
- cln1∆ cln2∆ clb5∆ clb6∆
- cln1∆ cln2∆ cln3∆
- cln1∆ cln2∆ cln3∆ GAL-CLN2
- cln1∆ cln2∆ cln3∆ GAL-CLN3
- cln1∆ cln2∆ cln3∆ sic1∆
- cln1∆ cln2∆ cln3∆ cdh1∆
- cln1∆ cln2∆ cln3∆ multi-copy CLB5
- cln1∆ cln2∆ cln3∆ GAL-CLB5
- cln1∆ cln2∆ cln3∆ multicopy BCK2
- cln1∆ cln2∆ cln3∆ GAL-CLB2
- cln1∆ cln2∆ cln3∆ apc-ts
- GAL-SIC1 cln1∆ cln2∆
- GAL-SIC1 GAL-CLN2 cln1∆ cln2∆
- GAL-SIC1 cln1∆ cln2∆ cdh1∆
- GAL-SIC1 GAL-CLN2 cln1∆ cln2∆ cdh1∆
- GAL-CLN2 cln1∆ cln2∆ cdh1∆
- GAL-CLN2 cln1∆ cln2∆
- cdc14-ts GAL-CLN2
- cln3∆
- cln3∆ bck2∆
- cln3∆ bck2∆ GAL-CLN2 cln1∆ cln2∆
- cln3∆ bck2∆ multi-copy CLN2
- cln3∆ bck2∆ sic1∆
- GAL-CLN3
cln1∆ cln2∆ cln3∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: ksn2'=ksn2"=0, Dn3=0.
Length of G1 phase: 227 min.
Arrest: G1 arrest according to our rule (see below).
Experiments:
Richardson, H., Wittenberg, C., Cross, F.R. and Reed, S.I. (1989). An essential G1 function for cyclin-like proteins in yeast. Cell 59:1127-1133.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Inviable, G1 arrest.
A cell must reach [ORI]=1 before the time it takes for a wild type cell in the same medium to divide twice (202.4 min in glucose and 293.4 min in galactose), otherwise it is considered G1-arrested.